Compelling Evidence Linking CD40 Gene With Graves’ Disease in the Chinese Han Population

Compelling Evidence Linking CD40 Gene With Graves’ Disease in the Chinese Han Population

Mutations in CD40 have been widely reported to be risk factors for Graves’ disease (GD). The gene, along with its cognate ligand CD40L, may regulate pro-inflammatory and immune responses. Rs1883832, located at the -1 position of the Kozak sequence, is the most well-studied single nucleotide polymorp...

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Main Authors: He Jiang, Fei-Fei Yuan, Hai-Ning Wang, Wei Liu, Xiao-Ping Ye, Shao-Ying Yang, Hui-Jun Xie, Sha-Sha Yu, Yu-Ru Ma, Le-Le Zhang, Shuang-Xia Zhao, Huai-Dong Song, The China Consortium for the Genetics of Autoimmune Thyroid Disease
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
Graves’ disease
single nucleotide polymorphisms
CD40
association analysis
expression quantitative trait locus
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Online Access:https://doaj.org/article/cf205bfd803540a3a5e7d83459702134
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https://doaj.org/article/cf205bfd803540a3a5e7d83459702134

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