Next-generation unnatural monosaccharides reveal that ESRRB O-GlcNAcylation regulates pluripotency of mouse embryonic stem cells
Per-O-acetylated unnatural monosaccharides are popular tools for glycan labeling in live cells but can undergo unwanted side reactions with cysteines. Here, the authors develop unnatural sugars in a partially esterified form that are inert towards cysteines, and use them to probe O-GlcNAcylation in...
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Auteurs principaux: | , , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2019
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Accès en ligne: | https://doaj.org/article/cf360d76d7754dd9bc90b461c1601791 |
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