Next-generation unnatural monosaccharides reveal that ESRRB O-GlcNAcylation regulates pluripotency of mouse embryonic stem cells

Per-O-acetylated unnatural monosaccharides are popular tools for glycan labeling in live cells but can undergo unwanted side reactions with cysteines. Here, the authors develop unnatural sugars in a partially esterified form that are inert towards cysteines, and use them to probe O-GlcNAcylation in...

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Auteurs principaux: Yi Hao, Xinqi Fan, Yujie Shi, Che Zhang, De-en Sun, Ke Qin, Wei Qin, Wen Zhou, Xing Chen
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/cf360d76d7754dd9bc90b461c1601791
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