Next-generation unnatural monosaccharides reveal that ESRRB O-GlcNAcylation regulates pluripotency of mouse embryonic stem cells
Per-O-acetylated unnatural monosaccharides are popular tools for glycan labeling in live cells but can undergo unwanted side reactions with cysteines. Here, the authors develop unnatural sugars in a partially esterified form that are inert towards cysteines, and use them to probe O-GlcNAcylation in...
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Autores principales: | Yi Hao, Xinqi Fan, Yujie Shi, Che Zhang, De-en Sun, Ke Qin, Wei Qin, Wen Zhou, Xing Chen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/cf360d76d7754dd9bc90b461c1601791 |
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