Cryo-EM structure of aerolysin variants reveals a novel protein fold and the pore-formation process
Aerolysin is a secreted bacterial pore forming toxin that inserts into the host plasma membrane, potentially leading to cell death. Here the authors present Cryo-EM structures of aerolysin arrested at different stages of the pore formation process that provide insight into the conformational changes...
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Auteurs principaux: | Ioan Iacovache, Sacha De Carlo, Nuria Cirauqui, Matteo Dal Peraro, F. Gisou van der Goot, Benoît Zuber |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2016
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Accès en ligne: | https://doaj.org/article/cf673eee03eb4a2b9b6bf3aad1ad1011 |
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