Development and characterization of patient-derived xenografts from non-small cell lung cancer brain metastases

Development and characterization of patient-derived xenografts from non-small cell lung cancer brain metastases

Abstract Non-small cell lung cancer (NSCLC) brain metastasis cell lines and in vivo models are not widely accessible. Herein we report on a direct-from patient-derived xenograft (PDX) model system of NSCLC brain metastases with genomic annotation useful for translational and mechanistic studies. Bot...

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Autores principales: Andrew M. Baschnagel, Saakshi Kaushik, Arda Durmaz, Steve Goldstein, Irene M. Ong, Lindsey Abel, Paul A. Clark, Zafer Gurel, Ticiana Leal, Darya Buehler, Gopal Iyer, Jacob G. Scott, Randall J. Kimple
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/cf6bf8b2cb75421fa4dbf71ed4ff419a
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https://doaj.org/article/cf6bf8b2cb75421fa4dbf71ed4ff419a

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