Poly(I:C)-Induced Mesenchymal Stem Cells Protect the Kidney Against Ischemia/Reperfusion Injury via the TLR3/PI3K Pathway

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Poly(I:C)-Induced Mesenchymal Stem Cells Protect the Kidney Against Ischemia/Reperfusion Injury via the TLR3/PI3K Pathway

Objective: To investigate the effect and protective mechanism of mesenchymal stem cell subpopulations on acute kidney injury by establishing a mouse model of renal ischemia-reperfusion injury.Methods: Male C57BL/6 mice were randomly divided into five groups, namely, sham-operation group and those tr...

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Bibliographic Details
Main Authors:	Tian Chen, Yamei Jiang, Shihao Xu, Yin Celeste Cheuk, Jiyan Wang, Cheng Yang, Ruiming Rong
Format:	article
Language:	EN
Published:	Frontiers Media S.A. 2021
Subjects:	acute kidney injury renal ischemia-reperfusion injury mesenchymal stem cell polyinosinic-polycytidylic acid anti-inflammatory phenotype Medicine (General) R5-920
Online Access:	https://doaj.org/article/cf839773cf0345f78f41ddb208f8abdd
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