Ketogal Safety Profile in Human Primary Colonic Epithelial Cells and in Mice

Ketogal Safety Profile in Human Primary Colonic Epithelial Cells and in Mice

In our previous studies, a ketorolac–galactose conjugate (ketogal) showed prolonged anti-inflammatory and analgesic activity, causing less gastric ulcerogenic effect and renal toxicity than its parent drug ketorolac. In order to demonstrate the safer profile of ketogal compared to ketorolac, histopa...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Federica Sodano, Bice Avallone, Monica Tizzano, Chiara Fogliano, Barbara Rolando, Elena Gazzano, Chiara Riganti, Salvatore Magliocca, Mariarosaria Cuozzo, Stefania Albrizio, Antonio Calignano, Claudia Cristiano, Roberto Russo, Maria Grazia Rimoli
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
ketorolac
ketogal
histological evaluation
colonic cytotoxicity
mitochondrial oxidative stress
Medicine
R
Pharmacy and materia medica
RS1-441
Acceso en línea:https://doaj.org/article/cfc1f4c4e463400faf7872078583b19b
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/cfc1f4c4e463400faf7872078583b19b

Ejemplares similares