Ketogal Safety Profile in Human Primary Colonic Epithelial Cells and in Mice
In our previous studies, a ketorolac–galactose conjugate (ketogal) showed prolonged anti-inflammatory and analgesic activity, causing less gastric ulcerogenic effect and renal toxicity than its parent drug ketorolac. In order to demonstrate the safer profile of ketogal compared to ketorolac, histopa...
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Autores principales: | Federica Sodano, Bice Avallone, Monica Tizzano, Chiara Fogliano, Barbara Rolando, Elena Gazzano, Chiara Riganti, Salvatore Magliocca, Mariarosaria Cuozzo, Stefania Albrizio, Antonio Calignano, Claudia Cristiano, Roberto Russo, Maria Grazia Rimoli |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/cfc1f4c4e463400faf7872078583b19b |
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