Joint mouse–human phenome-wide association to test gene function and disease risk

Phenome-wide association is a novel method that links sequence variants to a spectrum of phenotypes and diseases. Here the authors generate detailed mouse genetic and phenome data which links their phenome-wide association study (PheWAS) of mouse to corresponding PheWAS in human.

Guardado en:

Detalles Bibliográficos
Autores principales:	Xusheng Wang, Ashutosh K. Pandey, Megan K. Mulligan, Evan G. Williams, Khyobeni Mozhui, Zhengsheng Li, Virginija Jovaisaite, L. Darryl Quarles, Zhousheng Xiao, Jinsong Huang, John A. Capra, Zugen Chen, William L. Taylor, Lisa Bastarache, Xinnan Niu, Katherine S. Pollard, Daniel C. Ciobanu, Alexander O. Reznik, Artem V. Tishkov, Igor B. Zhulin, Junmin Peng, Stanley F. Nelson, Joshua C. Denny, Johan Auwerx, Lu Lu, Robert W. Williams
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/cfc59303336541d2b8ee796f1a6ebb5b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:cfc59303336541d2b8ee796f1a6ebb5b
record_format	dspace
spelling	oai:doaj.org-article:cfc59303336541d2b8ee796f1a6ebb5b2021-12-02T15:35:46ZJoint mouse–human phenome-wide association to test gene function and disease risk10.1038/ncomms104642041-1723https://doaj.org/article/cfc59303336541d2b8ee796f1a6ebb5b2016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10464https://doaj.org/toc/2041-1723Phenome-wide association is a novel method that links sequence variants to a spectrum of phenotypes and diseases. Here the authors generate detailed mouse genetic and phenome data which links their phenome-wide association study (PheWAS) of mouse to corresponding PheWAS in human.Xusheng WangAshutosh K. PandeyMegan K. MulliganEvan G. WilliamsKhyobeni MozhuiZhengsheng LiVirginija JovaisaiteL. Darryl QuarlesZhousheng XiaoJinsong HuangJohn A. CapraZugen ChenWilliam L. TaylorLisa BastaracheXinnan NiuKatherine S. PollardDaniel C. CiobanuAlexander O. ReznikArtem V. TishkovIgor B. ZhulinJunmin PengStanley F. NelsonJoshua C. DennyJohan AuwerxLu LuRobert W. WilliamsNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xusheng Wang Ashutosh K. Pandey Megan K. Mulligan Evan G. Williams Khyobeni Mozhui Zhengsheng Li Virginija Jovaisaite L. Darryl Quarles Zhousheng Xiao Jinsong Huang John A. Capra Zugen Chen William L. Taylor Lisa Bastarache Xinnan Niu Katherine S. Pollard Daniel C. Ciobanu Alexander O. Reznik Artem V. Tishkov Igor B. Zhulin Junmin Peng Stanley F. Nelson Joshua C. Denny Johan Auwerx Lu Lu Robert W. Williams Joint mouse–human phenome-wide association to test gene function and disease risk
description	Phenome-wide association is a novel method that links sequence variants to a spectrum of phenotypes and diseases. Here the authors generate detailed mouse genetic and phenome data which links their phenome-wide association study (PheWAS) of mouse to corresponding PheWAS in human.
format	article
author	Xusheng Wang Ashutosh K. Pandey Megan K. Mulligan Evan G. Williams Khyobeni Mozhui Zhengsheng Li Virginija Jovaisaite L. Darryl Quarles Zhousheng Xiao Jinsong Huang John A. Capra Zugen Chen William L. Taylor Lisa Bastarache Xinnan Niu Katherine S. Pollard Daniel C. Ciobanu Alexander O. Reznik Artem V. Tishkov Igor B. Zhulin Junmin Peng Stanley F. Nelson Joshua C. Denny Johan Auwerx Lu Lu Robert W. Williams
author_facet	Xusheng Wang Ashutosh K. Pandey Megan K. Mulligan Evan G. Williams Khyobeni Mozhui Zhengsheng Li Virginija Jovaisaite L. Darryl Quarles Zhousheng Xiao Jinsong Huang John A. Capra Zugen Chen William L. Taylor Lisa Bastarache Xinnan Niu Katherine S. Pollard Daniel C. Ciobanu Alexander O. Reznik Artem V. Tishkov Igor B. Zhulin Junmin Peng Stanley F. Nelson Joshua C. Denny Johan Auwerx Lu Lu Robert W. Williams
author_sort	Xusheng Wang
title	Joint mouse–human phenome-wide association to test gene function and disease risk
title_short	Joint mouse–human phenome-wide association to test gene function and disease risk
title_full	Joint mouse–human phenome-wide association to test gene function and disease risk
title_fullStr	Joint mouse–human phenome-wide association to test gene function and disease risk
title_full_unstemmed	Joint mouse–human phenome-wide association to test gene function and disease risk
title_sort	joint mouse–human phenome-wide association to test gene function and disease risk
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/cfc59303336541d2b8ee796f1a6ebb5b
work_keys_str_mv	AT xushengwang jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT ashutoshkpandey jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT megankmulligan jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT evangwilliams jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT khyobenimozhui jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT zhengshengli jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT virginijajovaisaite jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT ldarrylquarles jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT zhoushengxiao jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT jinsonghuang jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT johnacapra jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT zugenchen jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT williamltaylor jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT lisabastarache jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT xinnanniu jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT katherinespollard jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT danielcciobanu jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT alexanderoreznik jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT artemvtishkov jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT igorbzhulin jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT junminpeng jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT stanleyfnelson jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT joshuacdenny jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT johanauwerx jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT lulu jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk AT robertwwilliams jointmousehumanphenomewideassociationtotestgenefunctionanddiseaserisk
_version_	1718386503517732864

Joint mouse–human phenome-wide association to test gene function and disease risk

Ejemplares similares