Gene Therapy Strategy for Alzheimer’s and Parkinson’s Diseases Aimed at Preventing the Formation of Neurotoxic Oligomers in SH-SY5Y Cells

We present here a gene therapy approach aimed at preventing the formation of Ca<sup>2+</sup>-permeable amyloid pore oligomers that are considered as the most neurotoxic structures in both Alzheimer’s and Parkinson’s diseases. Our study is based on the design of a small peptide inhibitor...

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Bibliographic Details
Main Authors: Assou El-Battari, Léa Rodriguez, Henri Chahinian, Olivier Delézay, Jacques Fantini, Nouara Yahi, Coralie Di Scala
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/cfcd4cf4f97b44cfbbb6ba7ca40c603c
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