Gene Therapy Strategy for Alzheimer’s and Parkinson’s Diseases Aimed at Preventing the Formation of Neurotoxic Oligomers in SH-SY5Y Cells
We present here a gene therapy approach aimed at preventing the formation of Ca<sup>2+</sup>-permeable amyloid pore oligomers that are considered as the most neurotoxic structures in both Alzheimer’s and Parkinson’s diseases. Our study is based on the design of a small peptide inhibitor...
Enregistré dans:
Auteurs principaux: | Assou El-Battari, Léa Rodriguez, Henri Chahinian, Olivier Delézay, Jacques Fantini, Nouara Yahi, Coralie Di Scala |
---|---|
Format: | article |
Langue: | EN |
Publié: |
MDPI AG
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/cfcd4cf4f97b44cfbbb6ba7ca40c603c |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Microbiota-Derived β-Amyloid-like Peptides Trigger Alzheimer’s Disease-Related Pathways in the SH-SY5Y Neural Cell Line
par: Aitor Blanco-Míguez, et autres
Publié: (2021) -
Plasma Amyloid-β Oligomerization Tendency Predicts Amyloid PET Positivity
par: Pyun JM, et autres
Publié: (2021) -
The structure of gangliosides hides a code for determining neuronal functions
par: Giulia Lunghi, et autres
Publié: (2021) -
Síndrome anti-GQ1b: Descripción de cuatro pacientes y revisión de la literatura
par: Uribe S.M,Reinaldo, et autres
Publié: (2013) -
Causative factors for formation of toxic islet amyloid polypeptide oligomer in type 2 diabetes mellitus
par: Jeong HR, et autres
Publié: (2015)