UPF1 promotes the formation of R loops to stimulate DNA double-strand break repair
R loops are formed when single-stranded RNA anneals to one strand of DNA, forming three-stranded structures containing DNA-RNA hybrids and the displaced non-template single-stranded DNA. Here the authors reveal that the DNA:RNA helicase UPF1 plays a role in promoting R loops formation at telomeric d...
Guardado en:
Autores principales: | Greg H. P. Ngo, Julia W. Grimstead, Duncan M. Baird |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/cfce330374694ea4bad27a13a3243c22 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
An OB-fold complex controls the repair pathways for DNA double-strand breaks
por: Shengxian Gao, et al.
Publicado: (2018) -
The cohesin-like RecN protein stimulates RecA-mediated recombinational repair of DNA double-strand breaks
por: Lee A. Uranga, et al.
Publicado: (2017) -
Distribution of Holliday junctions and repair forks during Escherichia coli DNA double-strand break repair.
por: Tahirah Yasmin, et al.
Publicado: (2021) -
Rif1 S-acylation mediates DNA double-strand break repair at the inner nuclear membrane
por: Gabriele A. Fontana, et al.
Publicado: (2019) -
Structural basis for proficient oxidized ribonucleotide insertion in double strand break repair
por: Joonas A. Jamsen, et al.
Publicado: (2021)