An evaluation of the self-assembly enhancing properties of cell-derived hexameric amyloid-β
Abstract A key hallmark of Alzheimer’s disease is the extracellular deposition of amyloid plaques composed primarily of the amyloidogenic amyloid-β (Aβ) peptide. The Aβ peptide is a product of sequential cleavage of the Amyloid Precursor Protein, the first step of which gives rise to a C-terminal Fr...
Guardado en:
Autores principales: | Devkee M. Vadukul, Céline Vrancx, Pierre Burguet, Sabrina Contino, Nuria Suelves, Louise C. Serpell, Loïc Quinton, Pascal Kienlen-Campard |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/cffde72cfd7a458c9a29c038453f9d37 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Overexpression of wild-type human amyloid precursor protein alters GABAergic transmission
por: Anna Kreis, et al.
Publicado: (2021) -
Nano-assembly of amyloid β peptide: role of the hairpin fold
por: Sibaprasad Maity, et al.
Publicado: (2017) -
Cerebral vascular amyloid seeds drive amyloid β-protein fibril assembly with a distinct anti-parallel structure
por: Feng Xu, et al.
Publicado: (2016) -
Interconvertible vanadium-seamed hexameric pyrogallol[4]arene nanocapsules
por: Kongzhao Su, et al.
Publicado: (2018) -
Structure and activation mechanism of the hexameric plasma membrane H+-ATPase
por: Peng Zhao, et al.
Publicado: (2021)