An accomplice more than a mere victim: The impact of β-cell ER stress on type 1 diabetes pathogenesis
Background: Pancreatic β-cells are the insulin factory of an organism with a mission to regulate glucose homeostasis in the body. Due to their high secretory activity, β-cells rely on a functional and intact endoplasmic reticulum (ER). Perturbations to ER homeostasis and unmitigated stress lead to β...
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| Auteurs principaux: | , , |
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| Format: | article |
| Langue: | EN |
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Elsevier
2021
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| Accès en ligne: | https://doaj.org/article/cffe1661c7714398ae1a70141d83d43b |
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