Cholesterol loading suppresses the atheroinflammatory gene polarization of human macrophages induced by colony stimulating factors
Abstract In atherosclerotic lesions, blood-derived monocytes differentiate into distinct macrophage subpopulations, and further into cholesterol-filled foam cells under a complex milieu of cytokines, which also contains macrophage-colony stimulating factor (M-CSF) and granulocyte–macrophage-colony s...
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Autores principales: | Jani Lappalainen, Nicolas Yeung, Su D. Nguyen, Matti Jauhiainen, Petri T. Kovanen, Miriam Lee-Rueckert |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/d024a2c8f799481abd06e448627a9d01 |
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