Cholesterol loading suppresses the atheroinflammatory gene polarization of human macrophages induced by colony stimulating factors
Abstract In atherosclerotic lesions, blood-derived monocytes differentiate into distinct macrophage subpopulations, and further into cholesterol-filled foam cells under a complex milieu of cytokines, which also contains macrophage-colony stimulating factor (M-CSF) and granulocyte–macrophage-colony s...
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Main Authors: | , , , , , |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/d024a2c8f799481abd06e448627a9d01 |
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