An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation

Invasive non-typhoidal Salmonella (iNTS) infections are dominated by antibiotic resistant isolates of the sequence type (ST) 313. Here, the authors identify the ST313 sublineage II.1 in the Democratic Republic of the Congo exhibiting extensive drug resistance and genetic signatures potentially assoc...

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Autores principales: Sandra Van Puyvelde, Derek Pickard, Koen Vandelannoote, Eva Heinz, Barbara Barbé, Tessa de Block, Simon Clare, Eve L. Coomber, Katherine Harcourt, Sushmita Sridhar, Emily A. Lees, Nicole E. Wheeler, Elizabeth J. Klemm, Laura Kuijpers, Lisette Mbuyi Kalonji, Marie-France Phoba, Dadi Falay, Dauly Ngbonda, Octavie Lunguya, Jan Jacobs, Gordon Dougan, Stijn Deborggraeve
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Publicado: Nature Portfolio 2019
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spelling oai:doaj.org-article:d03041f0c2d4477dbba22683cea763a02021-12-02T14:38:38ZAn African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation10.1038/s41467-019-11844-z2041-1723https://doaj.org/article/d03041f0c2d4477dbba22683cea763a02019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11844-zhttps://doaj.org/toc/2041-1723Invasive non-typhoidal Salmonella (iNTS) infections are dominated by antibiotic resistant isolates of the sequence type (ST) 313. Here, the authors identify the ST313 sublineage II.1 in the Democratic Republic of the Congo exhibiting extensive drug resistance and genetic signatures potentially associated with host adaptation.Sandra Van PuyveldeDerek PickardKoen VandelannooteEva HeinzBarbara BarbéTessa de BlockSimon ClareEve L. CoomberKatherine HarcourtSushmita SridharEmily A. LeesNicole E. WheelerElizabeth J. KlemmLaura KuijpersLisette Mbuyi KalonjiMarie-France PhobaDadi FalayDauly NgbondaOctavie LunguyaJan JacobsGordon DouganStijn DeborggraeveNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sandra Van Puyvelde
Derek Pickard
Koen Vandelannoote
Eva Heinz
Barbara Barbé
Tessa de Block
Simon Clare
Eve L. Coomber
Katherine Harcourt
Sushmita Sridhar
Emily A. Lees
Nicole E. Wheeler
Elizabeth J. Klemm
Laura Kuijpers
Lisette Mbuyi Kalonji
Marie-France Phoba
Dadi Falay
Dauly Ngbonda
Octavie Lunguya
Jan Jacobs
Gordon Dougan
Stijn Deborggraeve
An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation
description Invasive non-typhoidal Salmonella (iNTS) infections are dominated by antibiotic resistant isolates of the sequence type (ST) 313. Here, the authors identify the ST313 sublineage II.1 in the Democratic Republic of the Congo exhibiting extensive drug resistance and genetic signatures potentially associated with host adaptation.
format article
author Sandra Van Puyvelde
Derek Pickard
Koen Vandelannoote
Eva Heinz
Barbara Barbé
Tessa de Block
Simon Clare
Eve L. Coomber
Katherine Harcourt
Sushmita Sridhar
Emily A. Lees
Nicole E. Wheeler
Elizabeth J. Klemm
Laura Kuijpers
Lisette Mbuyi Kalonji
Marie-France Phoba
Dadi Falay
Dauly Ngbonda
Octavie Lunguya
Jan Jacobs
Gordon Dougan
Stijn Deborggraeve
author_facet Sandra Van Puyvelde
Derek Pickard
Koen Vandelannoote
Eva Heinz
Barbara Barbé
Tessa de Block
Simon Clare
Eve L. Coomber
Katherine Harcourt
Sushmita Sridhar
Emily A. Lees
Nicole E. Wheeler
Elizabeth J. Klemm
Laura Kuijpers
Lisette Mbuyi Kalonji
Marie-France Phoba
Dadi Falay
Dauly Ngbonda
Octavie Lunguya
Jan Jacobs
Gordon Dougan
Stijn Deborggraeve
author_sort Sandra Van Puyvelde
title An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation
title_short An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation
title_full An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation
title_fullStr An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation
title_full_unstemmed An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation
title_sort african salmonella typhimurium st313 sublineage with extensive drug-resistance and signatures of host adaptation
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/d03041f0c2d4477dbba22683cea763a0
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