Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted rat hearts
Heart grafts need good vascularization to survive. Here, the authors engineer perfusable constructs of human embryonic stem cell-derived endothelial cells seeded in collagen matrix in patterned microchannels that form anastomosed vessels in vitro and have increased coronary vascular perfusion on tra...
Saved in:
Main Authors: | Meredith A. Redd, Nicole Zeinstra, Wan Qin, Wei Wei, Amy Martinson, Yuliang Wang, Ruikang K. Wang, Charles E. Murry, Ying Zheng |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
|
Subjects: | |
Online Access: | https://doaj.org/article/d0353d4f8b0744d1a71917d43e8a02a6 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Insulin-mediated muscle microvascular perfusion and its phenotypic predictors in humans
by: Kaitlin M. Love, et al.
Published: (2021) -
Deeper penetration of erythrocytes into the endothelial glycocalyx is associated with impaired microvascular perfusion.
by: Dae Hyun Lee, et al.
Published: (2014) -
Molecular and cellular basis of microvascular perfusion deficits induced by Clostridium perfringens and Clostridium septicum.
by: Michael J Hickey, et al.
Published: (2008) -
The application of tissue-engineered fish swim bladder vascular graft
by: Hualong Bai, et al.
Published: (2021) -
Rapid fabrication of reinforced and cell-laden vascular grafts structurally inspired by human coronary arteries
by: Tamara L. Akentjew, et al.
Published: (2019)