Structural basis for the ABO blood-group dependence of Plasmodium falciparum rosetting.

Structural basis for the ABO blood-group dependence of Plasmodium falciparum rosetting.

The ABO blood group influences susceptibility to severe Plasmodium falciparum malaria. Recent evidence indicates that the protective effect of group O operates by virtue of reduced rosetting of infected red blood cells (iRBCs) with uninfected RBCs. Rosetting is mediated by a subgroup of PfEMP1 adhes...

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Bibliographic Details
Main Authors: Inès Vigan-Womas, Micheline Guillotte, Alexandre Juillerat, Audrey Hessel, Bertrand Raynal, Patrick England, Jacques H Cohen, Olivier Bertrand, Thierry Peyrard, Graham A Bentley, Anita Lewit-Bentley, Odile Mercereau-Puijalon
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/d0409c6651fb4a2d9ca02f49988aadf0
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