Single cell imaging and quantification of TDP-43 and α-synuclein intercellular propagation
Abstract The intercellular spreading of protein assemblies is a major factor in the progression of neurodegenerative disorders. The quantitative study and visualization of cell-to-cell propagation using tagged-proteins is challenging due to the steric effect of relatively large fluorescence tags and...
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Autores principales: | , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/d049f33829294b88ae864baa009409c9 |
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