The histone chaperone FACT facilitates heterochromatin spreading by regulating histone turnover and H3K9 methylation states
Summary: Heterochromatin formation requires three distinct steps: nucleation, self-propagation (spreading) along the chromosome, and faithful maintenance after each replication cycle. Impeding any of those steps induces heterochromatin defects and improper gene expression. The essential histone chap...
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| Auteurs principaux: | , , , , , , , |
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| Format: | article |
| Langue: | EN |
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Elsevier
2021
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| Accès en ligne: | https://doaj.org/article/d053a21db4ae458c81001d81be4d5d4d |
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