A new view of the lethal apoptotic pore.

Cell death by apoptosis is indispensable for proper development and tissue homeostasis in all multicellular organisms, and its deregulation plays a key role in cancer and many other diseases. A crucial event in apoptosis is the formation of protein-permeable pores in the outer mitochondrial membrane...

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Autores principales: Gorka Basañez, Lucian Soane, J Marie Hardwick
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/d06e94dfc07a43579177eb136fbb76e8
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