Tumor Lymphatic Interactions Induce CXCR2-CXCL5 Axis and Alter Cellular Metabolism and Lymphangiogenic Pathways to Promote Cholangiocarcinoma

Cholangiocarcinoma (CCA), or cancer of bile duct epithelial cells, is a very aggressive malignancy characterized by early lymphangiogenesis in the tumor microenvironment (TME) and lymph node (LN) metastasis which correlate with adverse patient outcome. However, the specific roles of lymphatic endoth...

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Bibliographic Details
Main Authors:	Sukanya Roy, Subhashree Kumaravel, Priyanka Banerjee, Tori K. White, April O’Brien, Catherine Seelig, Rahul Chauhan, Burcin Ekser, Kayla J. Bayless, Gianfranco Alpini, Shannon S. Glaser, Sanjukta Chakraborty
Format:	article
Language:	EN
Published:	MDPI AG 2021
Subjects:	chemokines liver cancer lymphatic metastasis inflammation bioenergetics Biology (General) QH301-705.5
Online Access:	https://doaj.org/article/d07c1d18d4ff4f769fd2064703464d10
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Tumor Lymphatic Interactions Induce CXCR2-CXCL5 Axis and Alter Cellular Metabolism and Lymphangiogenic Pathways to Promote Cholangiocarcinoma

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