Interferon tau alleviates obesity-induced adipose tissue inflammation and insulin resistance by regulating macrophage polarization.

Chronic adipose tissue inflammation is a hallmark of obesity-induced insulin resistance and anti-inflammatory agents can benefit patients with obesity-associated syndromes. Currently available type I interferons for therapeutic immunomodulation are accompanied by high cytotoxicity and therefore in t...

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Auteurs principaux: Wei Ying, Srikanth Kanameni, Cheng-An Chang, Vijayalekshmi Nair, Stephen Safe, Fuller W Bazer, Beiyan Zhou
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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R
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Accès en ligne:https://doaj.org/article/d0881167d56545139c0db1b89418b02a
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