Interferon tau alleviates obesity-induced adipose tissue inflammation and insulin resistance by regulating macrophage polarization.
Chronic adipose tissue inflammation is a hallmark of obesity-induced insulin resistance and anti-inflammatory agents can benefit patients with obesity-associated syndromes. Currently available type I interferons for therapeutic immunomodulation are accompanied by high cytotoxicity and therefore in t...
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Autores principales: | Wei Ying, Srikanth Kanameni, Cheng-An Chang, Vijayalekshmi Nair, Stephen Safe, Fuller W Bazer, Beiyan Zhou |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/d0881167d56545139c0db1b89418b02a |
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