Nanoscopic investigation of C9orf72 poly-GA oligomers on nuclear membrane disruption by a photoinducible platform

Glycine-alanine dipeptide repeats produced by the C9orf72 gene are proposed to cause neurotoxicity in related diseases, but is challenging to study experimentally. Here a photolabile cell-penetrating peptide allows superresolution imaging of the distribution and aggregation of a simple dipeptide whi...

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Autores principales: Hung-Ming Chien, Ruei-Yu He, Chi-Chang Lee, Yung-An Huang, I-Ju Hung, Kai-Ting Hou, Jye-Chian Hsiao, Po-Chao Lu, Diksha Agnihotri, Eric Hwang, Joseph Jen-Tse Huang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d0d8eaa2f8954cce873fb107a77d365a
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