Characterizing the Genomic Profile in High-Grade Gliomas: From Tumor Core to Peritumoral Brain Zone, Passing through Glioma-Derived Tumorspheres

Characterizing the Genomic Profile in High-Grade Gliomas: From Tumor Core to Peritumoral Brain Zone, Passing through Glioma-Derived Tumorspheres

Glioblastoma is an extremely heterogeneous disease. Treatment failure and tumor recurrence primarily reflect the presence in the tumor core (TC) of the glioma stem cells (GSCs), and secondly the contribution, still to be defined, of the peritumoral brain zone (PBZ). Using the array-CGH platform, we...

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Bibliographic Details
Main Authors: Martina Giambra, Eleonora Messuti, Andrea Di Cristofori, Clarissa Cavandoli, Raffaele Bruno, Raffaella Buonanno, Matilde Marzorati, Melissa Zambuto, Virginia Rodriguez-Menendez, Serena Redaelli, Carlo Giussani, Angela Bentivegna
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
glioblastoma
GBM
glioma stem cell
peritumoral brain zone
genomic profile
array-CGH
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/d0eab1a766b84731a42b72c7714bb437
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