Human Cortex Spheroid with a Functional Blood Brain Barrier for High-Throughput Neurotoxicity Screening and Disease Modeling
Abstract The integral selectivity characteristic of the blood brain barrier (BBB) limits therapeutic options for many neurologic diseases and disorders. Currently, very little is known about the mechanisms that govern the dynamic nature of the BBB. Recent reports have focused on the development and...
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Main Authors: | Goodwell Nzou, R. T. Wicks, E. E. Wicks, S. A. Seale, C. H. Sane, A. Chen, S. V. Murphy, J. D. Jackson, A. J. Atala |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Online Access: | https://doaj.org/article/d0f27afeb18f49458be4b285d482ac08 |
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