RECON-Dependent Inflammation in Hepatocytes Enhances <named-content content-type="genus-species">Listeria monocytogenes</named-content> Cell-to-Cell Spread

ABSTRACT The oxidoreductase RECON is a high-affinity cytosolic sensor of bacterium-derived cyclic dinucleotides (CDNs). CDN binding inhibits RECON’s enzymatic activity and subsequently promotes inflammation. In this study, we sought to characterize the effects of RECON on the infection cycle of the...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Adelle P. McFarland, Thomas P. Burke, Alexie A. Carletti, Rochelle C. Glover, Hannah Tabakh, Matthew D. Welch, Joshua J. Woodward
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://doaj.org/article/d0f59fdd2d6e471cbb8d6cd46b30c4e4
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!