RECON-Dependent Inflammation in Hepatocytes Enhances <named-content content-type="genus-species">Listeria monocytogenes</named-content> Cell-to-Cell Spread

ABSTRACT The oxidoreductase RECON is a high-affinity cytosolic sensor of bacterium-derived cyclic dinucleotides (CDNs). CDN binding inhibits RECON’s enzymatic activity and subsequently promotes inflammation. In this study, we sought to characterize the effects of RECON on the infection cycle of the...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Adelle P. McFarland, Thomas P. Burke, Alexie A. Carletti, Rochelle C. Glover, Hannah Tabakh, Matthew D. Welch, Joshua J. Woodward
Format: article
Langue:EN
Publié: American Society for Microbiology 2018
Sujets:
Accès en ligne:https://doaj.org/article/d0f59fdd2d6e471cbb8d6cd46b30c4e4
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires