Sustained delivery of IL-1Ra from PF127-gel reduces hyperglycemia in diabetic GK-rats.

Interleukin-1beta (IL-1β) is a major cause for induction of various inflammatory mechanisms that are decisively involved to provoke pathogenesis of type 2 diabetes mellitus (T2DM). Interleukin-1 receptor antagonist (IL-1Ra) a naturally occurring anti-inflammatory antagonist of IL-1β has been recentl...

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Bibliographic Details
Main Authors: Muhammad Sajid Hamid Akash, Kanwal Rehman, Hongying Sun, Shuqing Chen
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
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Online Access:https://doaj.org/article/d0ff3e78ab334979b5d5c7e84a5d565e
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