Sustained delivery of IL-1Ra from PF127-gel reduces hyperglycemia in diabetic GK-rats.
Interleukin-1beta (IL-1β) is a major cause for induction of various inflammatory mechanisms that are decisively involved to provoke pathogenesis of type 2 diabetes mellitus (T2DM). Interleukin-1 receptor antagonist (IL-1Ra) a naturally occurring anti-inflammatory antagonist of IL-1β has been recentl...
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Main Authors: | Muhammad Sajid Hamid Akash, Kanwal Rehman, Hongying Sun, Shuqing Chen |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/d0ff3e78ab334979b5d5c7e84a5d565e |
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