MSA: reproducible mutational signature attribution with confidence based on simulations
Abstract Background Mutational signatures proved to be a useful tool for identifying patterns of mutations in genomes, often providing valuable insights about mutagenic processes or normal DNA damage. De novo extraction of signatures is commonly performed using Non-Negative Matrix Factorisation meth...
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| Formato: | article |
| Lenguaje: | EN |
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BMC
2021
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| Acceso en línea: | https://doaj.org/article/d101f8dfde724132b54e2266d9c6cf30 |
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