High-order SNP combinations associated with complex diseases: efficient discovery, statistical power and functional interactions.

There has been increased interest in discovering combinations of single-nucleotide polymorphisms (SNPs) that are strongly associated with a phenotype even if each SNP has little individual effect. Efficient approaches have been proposed for searching two-locus combinations from genome-wide datasets....

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Autores principales: Gang Fang, Majda Haznadar, Wen Wang, Haoyu Yu, Michael Steinbach, Timothy R Church, William S Oetting, Brian Van Ness, Vipin Kumar
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/d1067285e52140b5a3f12c106ddfc5a6
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