High-order SNP combinations associated with complex diseases: efficient discovery, statistical power and functional interactions.
There has been increased interest in discovering combinations of single-nucleotide polymorphisms (SNPs) that are strongly associated with a phenotype even if each SNP has little individual effect. Efficient approaches have been proposed for searching two-locus combinations from genome-wide datasets....
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Autores principales: | , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2012
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Acceso en línea: | https://doaj.org/article/d1067285e52140b5a3f12c106ddfc5a6 |
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