High-order SNP combinations associated with complex diseases: efficient discovery, statistical power and functional interactions.
There has been increased interest in discovering combinations of single-nucleotide polymorphisms (SNPs) that are strongly associated with a phenotype even if each SNP has little individual effect. Efficient approaches have been proposed for searching two-locus combinations from genome-wide datasets....
Guardado en:
Autores principales: | Gang Fang, Majda Haznadar, Wen Wang, Haoyu Yu, Michael Steinbach, Timothy R Church, William S Oetting, Brian Van Ness, Vipin Kumar |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
|
Materias: | |
Acceso en línea: | https://doaj.org/article/d1067285e52140b5a3f12c106ddfc5a6 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
SNP discovery from transcriptome of the swimbladder of Takifugu rubripes.
por: Jun Cui, et al.
Publicado: (2014) -
SNP discovery and development of a high-density genotyping array for sunflower.
por: Eleni Bachlava, et al.
Publicado: (2012) -
De novo SNP discovery in the Scandinavian brown bear (Ursus arctos).
por: Anita J Norman, et al.
Publicado: (2013) -
SNP discovery with EST and NextGen sequencing in switchgrass (Panicum virgatum L.).
por: Elhan S Ersoz, et al.
Publicado: (2012) -
When whole-genome alignments just won't work: kSNP v2 software for alignment-free SNP discovery and phylogenetics of hundreds of microbial genomes.
por: Shea N Gardner, et al.
Publicado: (2013)