High efficiency ex vivo cloning of antigen-specific human effector T cells.

While cloned T cells are valuable tools for the exploration of immune responses against viruses and tumours, current cloning methods do not allow inferences to be made about the function and phenotype of a clone's in vivo precursor, nor can precise cloning efficiencies be calculated. Additional...

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Auteurs principaux: Michelle A Neller, Michael H-L Lai, Catherine M Lanagan, Linda E O'Connor, Antonia L Pritchard, Nathan R Martinez, Christopher W Schmidt
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/d11adaf970244ecea3c97633192bcdc9
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