A complex of Neuroplastin and Plasma Membrane Ca2+ ATPase controls T cell activation

A complex of Neuroplastin and Plasma Membrane Ca2+ ATPase controls T cell activation

Abstract The outcome of T cell activation is determined by mechanisms that balance Ca2+ influx and clearance. Here we report that murine CD4 T cells lacking Neuroplastin (Nptn −/−), an immunoglobulin superfamily protein, display elevated cytosolic Ca2+ and impaired post-stimulation Ca2+ clearance, a...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Mark Korthals, Kristina Langnaese, Karl-Heinz Smalla, Thilo Kähne, Rodrigo Herrera-Molina, Juliane Handschuh, Anne-Christin Lehmann, Dejan Mamula, Michael Naumann, Constanze Seidenbecher, Werner Zuschratter, Kerry Tedford, Eckart D. Gundelfinger, Dirk Montag, Klaus-Dieter Fischer, Ulrich Thomas
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/d130938189af4ca2b4aea89ebca3139c
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/d130938189af4ca2b4aea89ebca3139c

Ejemplares similares