DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis

Monozygotic (MZ) twins are ideal to study the influence of non-genetic factors on complex phenotypes. Here, Souren et al. perform an EWAS in peripheral blood mononuclear cells from 45 MZ twins discordant for multiple sclerosis and identify disease and treatment-associated epigenetic markers.

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Auteurs principaux: Nicole Y. Souren, Lisa A. Gerdes, Pavlo Lutsik, Gilles Gasparoni, Eduardo Beltrán, Abdulrahman Salhab, Tania Kümpfel, Dieter Weichenhan, Christoph Plass, Reinhard Hohlfeld, Jörn Walter
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/d13bea4583bf457d8527bd2789d3b02f
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