A granulin-like growth factor secreted by the carcinogenic liver fluke, Opisthorchis viverrini, promotes proliferation of host cells.

The human liver fluke, Opisthorchis viverrini, infects millions of people throughout south-east Asia and is a major cause of cholangiocarcinoma, or cancer of the bile ducts. The mechanisms by which chronic infection with O. viverrini results in cholangiocarcinogenesis are multi-factorial, but one su...

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Auteurs principaux: Michael J Smout, Thewarach Laha, Jason Mulvenna, Banchob Sripa, Sutas Suttiprapa, Alun Jones, Paul J Brindley, Alex Loukas
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2009
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Accès en ligne:https://doaj.org/article/d13e729afa514a02b859c69d092e9853
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