3D particle averaging and detection of macromolecular symmetry in localization microscopy

Adaptation of current algorithms to 3D SMLM data is currently problematic. Here the authors report a method that increases the signal-to-noise ratio and resolution of 3D single particle analysis in localization microscopy and enables determination of the symmetry groups of macromolecular complexes.

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Bibliographic Details
Main Authors: Hamidreza Heydarian, Maarten Joosten, Adrian Przybylski, Florian Schueder, Ralf Jungmann, Ben van Werkhoven, Jan Keller-Findeisen, Jonas Ries, Sjoerd Stallinga, Mark Bates, Bernd Rieger
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/d17ad19811dd4f2a9819d5862675ea69
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