A ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity
Synthetic methods that efficiently construct structurally diverse molecular scaffolds are attractive routes to diversely bioactive molecules. Here the authors report a method whereby common starting materials are converted to structurally and functionally diverse products by changing the catalyst li...
Guardado en:
Autores principales: | , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/d1bf46a4d848459f9c5dd08e325677dc |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:d1bf46a4d848459f9c5dd08e325677dc |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:d1bf46a4d848459f9c5dd08e325677dc2021-12-02T14:42:09ZA ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity10.1038/ncomms140432041-1723https://doaj.org/article/d1bf46a4d848459f9c5dd08e325677dc2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14043https://doaj.org/toc/2041-1723Synthetic methods that efficiently construct structurally diverse molecular scaffolds are attractive routes to diversely bioactive molecules. Here the authors report a method whereby common starting materials are converted to structurally and functionally diverse products by changing the catalyst ligand.Yen-Chun LeeSumersing PatilChristopher GolzCarsten StrohmannSlava ZieglerKamal KumarHerbert WaldmannNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Yen-Chun Lee Sumersing Patil Christopher Golz Carsten Strohmann Slava Ziegler Kamal Kumar Herbert Waldmann A ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity |
description |
Synthetic methods that efficiently construct structurally diverse molecular scaffolds are attractive routes to diversely bioactive molecules. Here the authors report a method whereby common starting materials are converted to structurally and functionally diverse products by changing the catalyst ligand. |
format |
article |
author |
Yen-Chun Lee Sumersing Patil Christopher Golz Carsten Strohmann Slava Ziegler Kamal Kumar Herbert Waldmann |
author_facet |
Yen-Chun Lee Sumersing Patil Christopher Golz Carsten Strohmann Slava Ziegler Kamal Kumar Herbert Waldmann |
author_sort |
Yen-Chun Lee |
title |
A ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity |
title_short |
A ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity |
title_full |
A ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity |
title_fullStr |
A ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity |
title_full_unstemmed |
A ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity |
title_sort |
ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/d1bf46a4d848459f9c5dd08e325677dc |
work_keys_str_mv |
AT yenchunlee aliganddirecteddivergentcatalyticapproachtoestablishstructuralandfunctionalscaffolddiversity AT sumersingpatil aliganddirecteddivergentcatalyticapproachtoestablishstructuralandfunctionalscaffolddiversity AT christophergolz aliganddirecteddivergentcatalyticapproachtoestablishstructuralandfunctionalscaffolddiversity AT carstenstrohmann aliganddirecteddivergentcatalyticapproachtoestablishstructuralandfunctionalscaffolddiversity AT slavaziegler aliganddirecteddivergentcatalyticapproachtoestablishstructuralandfunctionalscaffolddiversity AT kamalkumar aliganddirecteddivergentcatalyticapproachtoestablishstructuralandfunctionalscaffolddiversity AT herbertwaldmann aliganddirecteddivergentcatalyticapproachtoestablishstructuralandfunctionalscaffolddiversity AT yenchunlee liganddirecteddivergentcatalyticapproachtoestablishstructuralandfunctionalscaffolddiversity AT sumersingpatil liganddirecteddivergentcatalyticapproachtoestablishstructuralandfunctionalscaffolddiversity AT christophergolz liganddirecteddivergentcatalyticapproachtoestablishstructuralandfunctionalscaffolddiversity AT carstenstrohmann liganddirecteddivergentcatalyticapproachtoestablishstructuralandfunctionalscaffolddiversity AT slavaziegler liganddirecteddivergentcatalyticapproachtoestablishstructuralandfunctionalscaffolddiversity AT kamalkumar liganddirecteddivergentcatalyticapproachtoestablishstructuralandfunctionalscaffolddiversity AT herbertwaldmann liganddirecteddivergentcatalyticapproachtoestablishstructuralandfunctionalscaffolddiversity |
_version_ |
1718389781062221824 |