A ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity

Synthetic methods that efficiently construct structurally diverse molecular scaffolds are attractive routes to diversely bioactive molecules. Here the authors report a method whereby common starting materials are converted to structurally and functionally diverse products by changing the catalyst li...

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Autores principales: Yen-Chun Lee, Sumersing Patil, Christopher Golz, Carsten Strohmann, Slava Ziegler, Kamal Kumar, Herbert Waldmann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/d1bf46a4d848459f9c5dd08e325677dc
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spelling oai:doaj.org-article:d1bf46a4d848459f9c5dd08e325677dc2021-12-02T14:42:09ZA ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity10.1038/ncomms140432041-1723https://doaj.org/article/d1bf46a4d848459f9c5dd08e325677dc2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14043https://doaj.org/toc/2041-1723Synthetic methods that efficiently construct structurally diverse molecular scaffolds are attractive routes to diversely bioactive molecules. Here the authors report a method whereby common starting materials are converted to structurally and functionally diverse products by changing the catalyst ligand.Yen-Chun LeeSumersing PatilChristopher GolzCarsten StrohmannSlava ZieglerKamal KumarHerbert WaldmannNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yen-Chun Lee
Sumersing Patil
Christopher Golz
Carsten Strohmann
Slava Ziegler
Kamal Kumar
Herbert Waldmann
A ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity
description Synthetic methods that efficiently construct structurally diverse molecular scaffolds are attractive routes to diversely bioactive molecules. Here the authors report a method whereby common starting materials are converted to structurally and functionally diverse products by changing the catalyst ligand.
format article
author Yen-Chun Lee
Sumersing Patil
Christopher Golz
Carsten Strohmann
Slava Ziegler
Kamal Kumar
Herbert Waldmann
author_facet Yen-Chun Lee
Sumersing Patil
Christopher Golz
Carsten Strohmann
Slava Ziegler
Kamal Kumar
Herbert Waldmann
author_sort Yen-Chun Lee
title A ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity
title_short A ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity
title_full A ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity
title_fullStr A ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity
title_full_unstemmed A ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity
title_sort ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/d1bf46a4d848459f9c5dd08e325677dc
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