Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides

por Philipp M. Cromm, Sebastian Schaubach, Jochen Spiegel, Alois Fürstner, Tom N. Grossmann, Herbert Waldmann
Publicado 2016

A ligand-directed divergent catalytic approach to establish structural and functional scaffold diversity

por Yen-Chun Lee, Sumersing Patil, Christopher Golz, Carsten Strohmann, Slava Ziegler, Kamal Kumar, Herbert Waldmann
Publicado 2017

Natural product fragment combination to performance-diverse pseudo-natural products

por Michael Grigalunas, Annina Burhop, Sarah Zinken, Axel Pahl, José-Manuel Gally, Niklas Wild, Yannik Mantel, Sonja Sievers, Daniel J. Foley, Rebecca Scheel, Carsten Strohmann, Andrey P. Antonchick, Herbert Waldmann
Publicado 2021

Identification of pyrazolopyridazinones as PDEδ inhibitors

por Björn Papke, Sandip Murarka, Holger A Vogel, Pablo Martín-Gago, Marija Kovacevic, Dina C Truxius, Eyad K Fansa, Shehab Ismail, Gunther Zimmermann, Kaatje Heinelt, Carsten Schultz-Fademrecht, Alaa Al Saabi, Matthias Baumann, Peter Nussbaumer, Alfred Wittinghofer, Herbert Waldmann, Philippe I.H. Bastiaens
Publicado 2016

A protein tertiary structure mimetic modulator of the Hippo signalling pathway

por Hélène Adihou, Ranganath Gopalakrishnan, Tim Förster, Stéphanie M. Guéret, Raphael Gasper, Stefan Geschwindner, Carmen Carrillo García, Hacer Karatas, Ajaybabu V. Pobbati, Mercedes Vazquez‐Chantada, Paul Davey, Carola M. Wassvik, Jeremy Kah Sheng Pang, Boon Seng Soh, Wanjin Hong, Elisabetta Chiarparin, Dennis Schade, Alleyn T. Plowright, Eric Valeur, Malin Lemurell, Tom N. Grossmann, Herbert Waldmann
Publicado 2020