A Review of Natural Products for Prevention of Acute Kidney Injury

Background and Objectives: acute kidney injury (AKI), formerly called acute renal failure (ARF), is commonly defined as an abrupt decline in renal function, clinically manifesting as a reversible acute increase in nitrogen waste products—measured by blood urea nitrogen (BUN) and serum creatinine lev...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hyun Goo Kang, Hyun Ki Lee, Kyu Bong Cho, Sang Il Park
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	acute kidney injury prevention natural products antioxidant Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/d1e1ea71adc54d378217176d596014f2
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:d1e1ea71adc54d378217176d596014f2
record_format	dspace
spelling	oai:doaj.org-article:d1e1ea71adc54d378217176d596014f22021-11-25T18:19:05ZA Review of Natural Products for Prevention of Acute Kidney Injury10.3390/medicina571112661648-91441010-660Xhttps://doaj.org/article/d1e1ea71adc54d378217176d596014f22021-11-01T00:00:00Zhttps://www.mdpi.com/1648-9144/57/11/1266https://doaj.org/toc/1010-660Xhttps://doaj.org/toc/1648-9144Background and Objectives: acute kidney injury (AKI), formerly called acute renal failure (ARF), is commonly defined as an abrupt decline in renal function, clinically manifesting as a reversible acute increase in nitrogen waste products—measured by blood urea nitrogen (BUN) and serum creatinine levels—over the course of hours to weeks. AKI occurs in about 20% of all hospitalized patients and is more common in the elderly. Therefore, it is necessary to prevent the occurrence of AKI, and to detect and treat early, since it is known that a prolonged period of kidney injury increases cardiovascular complications and the risk of death. Despite advances in modern medicine, there are no consistent treatment strategies for preventing the progression to chronic kidney disease. Through many studies, the safety and efficacy of natural products have been proven, and based on this, the time and cost required for new drug development can be reduced. In addition, research results on natural products are highly anticipated in the prevention and treatment of various diseases. In relation to AKI, many papers have reported that many natural products can prevent and treat AKI. Conclusions: in this paper, the results of studies on natural products related to AKI were found and summarized, and the mechanism by which the efficacy of AKI was demonstrated was reviewed. Many natural products show that AKI can be prevented and treated, suggesting that these natural products can help to develop new drugs. In addition, we may be helpful to elucidate additional mechanisms and meta-analysis in future natural product studies.Hyun Goo KangHyun Ki LeeKyu Bong ChoSang Il ParkMDPI AGarticleacute kidney injurypreventionnatural productsantioxidantMedicine (General)R5-920ENMedicina, Vol 57, Iss 1266, p 1266 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	acute kidney injury prevention natural products antioxidant Medicine (General) R5-920
spellingShingle	acute kidney injury prevention natural products antioxidant Medicine (General) R5-920 Hyun Goo Kang Hyun Ki Lee Kyu Bong Cho Sang Il Park A Review of Natural Products for Prevention of Acute Kidney Injury
description	Background and Objectives: acute kidney injury (AKI), formerly called acute renal failure (ARF), is commonly defined as an abrupt decline in renal function, clinically manifesting as a reversible acute increase in nitrogen waste products—measured by blood urea nitrogen (BUN) and serum creatinine levels—over the course of hours to weeks. AKI occurs in about 20% of all hospitalized patients and is more common in the elderly. Therefore, it is necessary to prevent the occurrence of AKI, and to detect and treat early, since it is known that a prolonged period of kidney injury increases cardiovascular complications and the risk of death. Despite advances in modern medicine, there are no consistent treatment strategies for preventing the progression to chronic kidney disease. Through many studies, the safety and efficacy of natural products have been proven, and based on this, the time and cost required for new drug development can be reduced. In addition, research results on natural products are highly anticipated in the prevention and treatment of various diseases. In relation to AKI, many papers have reported that many natural products can prevent and treat AKI. Conclusions: in this paper, the results of studies on natural products related to AKI were found and summarized, and the mechanism by which the efficacy of AKI was demonstrated was reviewed. Many natural products show that AKI can be prevented and treated, suggesting that these natural products can help to develop new drugs. In addition, we may be helpful to elucidate additional mechanisms and meta-analysis in future natural product studies.
format	article
author	Hyun Goo Kang Hyun Ki Lee Kyu Bong Cho Sang Il Park
author_facet	Hyun Goo Kang Hyun Ki Lee Kyu Bong Cho Sang Il Park
author_sort	Hyun Goo Kang
title	A Review of Natural Products for Prevention of Acute Kidney Injury
title_short	A Review of Natural Products for Prevention of Acute Kidney Injury
title_full	A Review of Natural Products for Prevention of Acute Kidney Injury
title_fullStr	A Review of Natural Products for Prevention of Acute Kidney Injury
title_full_unstemmed	A Review of Natural Products for Prevention of Acute Kidney Injury
title_sort	review of natural products for prevention of acute kidney injury
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/d1e1ea71adc54d378217176d596014f2
work_keys_str_mv	AT hyungookang areviewofnaturalproductsforpreventionofacutekidneyinjury AT hyunkilee areviewofnaturalproductsforpreventionofacutekidneyinjury AT kyubongcho areviewofnaturalproductsforpreventionofacutekidneyinjury AT sangilpark areviewofnaturalproductsforpreventionofacutekidneyinjury AT hyungookang reviewofnaturalproductsforpreventionofacutekidneyinjury AT hyunkilee reviewofnaturalproductsforpreventionofacutekidneyinjury AT kyubongcho reviewofnaturalproductsforpreventionofacutekidneyinjury AT sangilpark reviewofnaturalproductsforpreventionofacutekidneyinjury
_version_	1718411348462796800

A Review of Natural Products for Prevention of Acute Kidney Injury

Ejemplares similares