SARS-CoV-2 Nsp5 Demonstrates Two Distinct Mechanisms Targeting RIG-I and MAVS To Evade the Innate Immune Response

SARS-CoV-2 Nsp5 Demonstrates Two Distinct Mechanisms Targeting RIG-I and MAVS To Evade the Innate Immune Response

The ongoing COVID-19 pandemic is caused by SARS-CoV-2, which is rapidly evolving with better transmissibility. Understanding the molecular basis of the SARS-CoV-2 interaction with host cells is of paramount significance, and development of antiviral agents provides new avenues to prevent and treat...

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Bibliographic Details
Main Authors: Yongzhen Liu, Chao Qin, Youliang Rao, Chau Ngo, Joshua J. Feng, Jun Zhao, Shu Zhang, Ting-Yu Wang, Jessica Carriere, Ali Can Savas, Mehrnaz Zarinfar, Stephanie Rice, Hanging Yang, Weiming Yuan, Julio A. Camarero, Jianhua Yu, Xiaojiang S. Chen, Chao Zhang, Pinghui Feng
Format: article
Language:EN
Published: American Society for Microbiology 2021
Subjects:
Microbiology
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Online Access:https://doaj.org/article/d1f591fa063b42b0b3faac6bdd373a47
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