Relacin, a novel antibacterial agent targeting the Stringent Response.
Finding bacterial cellular targets for developing novel antibiotics has become a major challenge in fighting resistant pathogenic bacteria. We present a novel compound, Relacin, designed to inhibit (p)ppGpp production by the ubiquitous bacterial enzyme RelA that triggers the Stringent Response. Rela...
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Auteurs principaux: | , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2012
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Accès en ligne: | https://doaj.org/article/d1f6e73e68eb43c99e4dd57e26c58e24 |
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