Computationally predicting clinical drug combination efficacy with cancer cell line screens and independent drug action

Computational models that can predict drug combination efficacy are often based on drug synergy. Here, the authors develop a different approach to computationally predict the efficacy of drug combinations using monotherapy data from high-throughput cancer cell line screens.

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Detalles Bibliográficos
Autores principales: Alexander Ling, R. Stephanie Huang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/d1fa96cd03394bc89c33eaee9b5d9687
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