Metabolic labelling of the carbohydrate core in bacterial peptidoglycan and its applications

N-acetyl-muramic acid (NAM) is a core component of the bacterial peptidoglycan (PG) cell wall, and is recognised by the innate immune system. Here the authors engineer Gram-negative and Gram-positive bacteria to incorporate a modified NAM into the backbone of PG, which can be labelled with click che...

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Autores principales: Hai Liang, Kristen E. DeMeester, Ching-Wen Hou, Michelle A. Parent, Jeffrey L. Caplan, Catherine L. Grimes
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/d2137f58154341eaa6ef192a234541b0
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