Metabolic labelling of the carbohydrate core in bacterial peptidoglycan and its applications
N-acetyl-muramic acid (NAM) is a core component of the bacterial peptidoglycan (PG) cell wall, and is recognised by the innate immune system. Here the authors engineer Gram-negative and Gram-positive bacteria to incorporate a modified NAM into the backbone of PG, which can be labelled with click che...
Guardado en:
Autores principales: | Hai Liang, Kristen E. DeMeester, Ching-Wen Hou, Michelle A. Parent, Jeffrey L. Caplan, Catherine L. Grimes |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/d2137f58154341eaa6ef192a234541b0 |
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