Development of adult worms and granulomatous pathology are collectively regulated by T- and B-cells in mice infected with Schistosoma japonicum.

Schistosoma blood flukes, which cause schistosomiasis affecting 200 million people in the world, are dependent on signals from host CD4(+) T cells to facilitate parasite growth and development in the mammalian host and to induce Th2-biased inflammatory granulomas. B cells, however, are reported to d...

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Auteurs principaux: Hongbin Tang, Zhenping Ming, Rong Liu, Tao Xiong, Christoph G Grevelding, Huifeng Dong, Mingsen Jiang
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/d22b11949f2243339e444cd8856c454c
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