Identification and functional characterization of novel phosphorylation sites in TAK1-binding protein (TAB) 1.

TAB1 was defined as a regulatory subunit of the protein kinase TAK1, which functions upstream in the pathways activated by interleukin (IL)-1, tumor necrosis factor (TNF), toll-like receptors (TLRs) and stressors. However, TAB1 also functions in the p38 MAPK pathway downstream of TAK1. We identified...

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Autores principales: Alexander Wolf, Knut Beuerlein, Christoph Eckart, Hendrik Weiser, Beate Dickkopf, Helmut Müller, Hiroaki Sakurai, Michael Kracht
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/d23bd930059944bfbde9b60250c2422f
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